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Neue Medikamente in Pipeline 2003

Fusionsprotein (CTLA4Ig) bei Rheumatoide Arthritis

Schlüsselwörter: Exenatid, Medikamente, Fusionsprotein, CTLA4Ig, Rheumatoide Arthritis und CTLA4-Rezeptor.

Fusionsprotein (CTLA4Ig) von Bristol-Myers Squibb: "Bei Patienten mit aktiver rheumatoider Arthritis kann ein neuer Wirkstoff, der die Proliferation von T-Zellen hemmt, in Kombination mit Methotrexat zu einer Verbesserung der Beschwerden führen (N Engl J Med 2003; 349: 1907–1915)...." Mehr im Ärzteblatt...

Bristol-Myers Squibb plant phase III-Studien für CTLA4Ig. Wir werden über die Wirkung und Nebenwirkungen des neuen Präparates nach einer Zulassung in Deutschland ausführlicher informieren.

Joel M. Kremer et al: Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig

Datum: 20.12.06.03

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	Neue-Medikamente-Index 2012 - 2002
CFTR-Corrector VX-708 Dapagliflozin (Forxiga) Vemurafenib (Zelboraf) Kombipille Nomegestrol (Zoely) Vandetanib (Caprelsa) Vorapaxar Peginesatid (Omontys) Euphorbia peplus (Picato) TAK-875-FFA1-Agonist Azilsartan (Edarbi) Rilpivirin (Edurant) Vismodegib Dexamfetamin (Attentin) AMG145 und REGN727 AMG145 und REGN727 Abirateron (Zytiga) Dexmedetomidin (Dexdor) Linagliptin (Trajenta) Telaprevir (Incivo) Rilpivirin Pegloticase (Krystexxa) Teriflunomid-ms Lebrikizumab Pirfenidon (Esbriet) Cytisin (Tabex) Tyrosinkinasehemmer BIBF 1120 Eculizumab (Soliris) Bromfenac (Yellox) Fampridin (Fampyra) Linaclotid Brentuximab/Vedotin (Adcetris) Ipilimumab (Vervoy) Belatacept (Nulojix®) Pitavastatin (Livazo) Dapagliflozin Bardoxolon Pasireotide Epoprostenol Xiapex Retigabin (Trobalt) Lavendelöl (Lasea) Belimumab (Benlysta) Degludec Eribulin (Halaven) Cabazitaxel (Jevtana) Edoxaban preladenant Hydroxy-Progesteron (Makena) Fidaxomicin (Dificlir, Dificid) Dapagliflozin Dalcetrapib Aleglitazar Naltrexon (Adepend) Ticagrelor (Brilique) Vernakalant (Brinavess) Asenapin (Sycrest) Bazedoxifen (Conbriza) Bilastin (Bitosen) Conestat alfa (Ruconest) Latrepirdin (Dimebon) Dronedaron (Multaq) Daclizumab (Zenapax) Prucaloprid (Resolor) Febuxostat (Adenuric) Mifamurtid (Mepact) Eprotirom Amifampridin (Firdapse) Telaprevir MDV3100 Corifollitropin alfa (Elonva) Tadalafil (Adcirca®) Histamindihydrochlorid (Ceplene) Ofatumumab (Arzerra) Denosumab (Prolia) Veregen-Salbe Silodosin (Urorec) Mipomersen Boceprevir und Telaprevir Glycopyrrolat (Cuvposa) Contrave: Naltrexon/Bupropion Lorcaserin Ticagrelor (Brilinta) Almorexant Tapentadol (Palexia) Tanezumab Fostamatinib Abirateron Ceftarolin (Teflaro) Tesamorelin (Egrifta) CFTR-Potenziator VX-770 Anacetrapib Aflibercept (VEGF-Trap-Eye) Micafungin (Mycamine) Rosuvastatin (Crestor) Telcagepant Mepolizumab Avotermin PSD502 Dexmedetomidin Dapoxetin (Priligy®) Ixiaro Synflorix Uricase (Krystexxa) Voglibose (Basen) Gamma-Sekretase-Inhibitor Catumaxomab (Removab) Degarelix (Firmagon) Qlaira Solanezumab: Alzheimer-Demenz-Impfung Belimumab (Benlysta) Liraglutid (Victoza) Histrelin (Vantas) Enzym Collagenase (Xiaflex) Apixaban (Eliquis) Ulipristalacetat (EllaOne®) Peramivir BRAF-Hemmer PLX4032 Pandemrix und Focetria zur Schweinegrippe-Impfung Celvapam®: Schweinegrippe-Impfstoff Laropiprant (Tredaptive) Plerixafor (Mozobil) Hematid Flibanserin Tranexansäure (Lysteda) Eslicarbazepinacetat (Zebinix®) Vinflunin (Javlor®) Golimumab (Simponi) Saxagliptin (Onglyza) Fluzone High-Dose (Fluzon) Canakinumab (Ilaris®) Darusentan Indacaterol (Onbrez® Breezhaler) Cladribin und Fingolimod
Taranabant Idraparinux S107 Antithrombin-III Stiripentol (Diacomit®) Desvenlafaxin Anidulafungin (Ecalta®) Epoetin delta (Dynepo®) Mecasermin (Increlex®) Colesevelam (Cholestagel®) Abarelix (Plenaxis®) Romiplostim ISA247 Melatonin (Circadin® Docosanol (Erazaban, Abreva) LY686017 (NK1R-Hemmer) Fosaprepitant-Dimeglumin (Ivemend®) Ustekinumab (Stelara) Methylnaltrexon (Relistor) Prucaloprid Ambrisentan (Volibris®) Tafluprost (Taflotan®) Terlipressin (Glycylpressin®, Haemopressin®) Droperidol (Xomolix®) Xarelto® Nalbuphin (Nalpain®) Rupatadin (Rupafin®) Zofenopril (Bifril®) Icatibant (Firazyr®) Rifaximin (Xifaxan®) Lacosamid (Vimpat®) Fesoterodin (Toviaz®) Doripenem (Doribax®) Tesofensin Boceprevir Etravirin (Intelence®) Sugammadex (Bridion®) Tasimelteon
BMS-201038 E75-Brustkrebs-Impfung MK-0518 Cervarix Darunavir (Prezista®) Tocilizumab (Actemra®) Fenretinide Sitaxentan (Thelin®) Pasireotid Oblimersen (Genasense®) Maraviroc Cilostazol (Pletal®) Fenoldopam (Corlopam®) Fenoldopam (Corlopam®) Tetrabenazin (Nitoman®) Alphanate® und Humate-P® Dauer-Pille Lybrel Ranolazin (Ranexa®) Rufinamid (Inovelon®) Mircera (C.E.R.A.) mGlu2/3-Rezeptor-Agonist Eplivanserin Ustekinumab Pitrakinra Prasugrel (Efient) Zoledronat (Aclasta®) ANP Piribedil (Clarium®) Tesamorelin Baclofen

Rotarix-Rotateq Deferasirox (Exjade®) Natriumoxybat (Xyrem®) Emtricitabin (Emtriva®) Argatroban (Argatra®) Dabigatran (Rendix) Denosumab Itoprid 11-valente-Vakzine Letrozol (Femara) Infliximab (Remicade®) Sildenafil (Revatio®) Bupropion (Elontril, Wellbutrin) Panitumumab (Vectibix) Tenofovir (Viread®) Herceptin® (Trastuzumab) Vareniclin (Chantix®) Imatinib (Glivec®) Rotigotin (Neupro®) CAIV-T-Impstoff Gardasil Vildagliptin Prostatakrebs-Impfung Sipuleucel-T Dasatinib (Sprycel) Nilotinib (Tasigna) Ranibizumab Gabapentin (Neurontin®) Pramipexol (Sifrol®) Ropinirol (Adartrel®) Paliperidon (Invega) Sertindol (Serdolect®) Tysabri (Natalizumab) TA-CD: Kokain-Impfung MK-0524 Nelarabin (Atriance®) Pazopanib (Votrient) Eltrombopaq (Revolade, Promacta) Casopitant Eculizumab (Alexion®) Prevenar Telbivudin Certolizumab Grazax Lumiracoxib (Prexige®) Tolvaptan (Samsca) Temsirolimus Darmkrebs-Impfstoff Reniale Rozerem (Ramelteon®) Agomelatin (Valdoxan®) Targin (Oxycodon und Naloxon)

Pegaptanib (Macugen®) Insulin Glulisin (Apidra®) Neuropeptid Melanocortin (MSH) Ixabepilon Rivastigmin (Exelon®) Modafinil (Vigil®) Darifenacin (Emselex®) Solifenacin (Vesicur®) GLP-1 Lapatinib AT-1001 Ciclesonid (Alvesco®) Rasagilin Aliskiren Lenalidomid Tositumomab (Bexxar) Alvimopan (Entrareg) NXY-059 (Cevovive) Tygacil® (Tigecyclin) DG031 Dapoxetine/Dapoxetin Nesiritide/Nesiritid Revatio Herpes-Zoster-Impfung Pertussis-Impfung Adlimumab (Humira) Integrin-AK Sativex Daclizumab (Zenapax®)) Cetuximab (Erbitux®) Topiramat (Topamax) Nikotin-Vakzine Pemetrexed (Alimta®) Phosphatidylcholin Topiramat Sitagliptin Abatacept Posaconazol Ropinirol Rivaroxaban (Xarelto®) Zonisamid (Zonegran®) Dronedaron Tarceva-Pankreaskrebs Sunitinib (Sutent) Bicalutamid (Casodex)

Daclizumab (Zenapax) Lamotrigin (Elmendos) Strontium Olanzapin (Zyprexa) Olopatadin (Opatanol) Epinastin (Relestat) Fulvestrant (Faslodex) CRGP-Antagonist Rimonabant Myfortic Emtricitabin (Emtriva) Inhalatives Insulin Pramlintid Oblimersen Regaine Frauen Torcetrapib Manidipin (Manyper) Reyataz (Atazanavir) Inegy Mabthera (Rituximab) Hamlet (BAY 43-9006 (Sorafenib) Infliximab (Remicade®) Erlotinib (Tarceva®) SU11248 Cinacalcet Pollenblocker Ruboxistaurin Levemir Angiox Alzheimer-Antikörper L-BlP25 Actinonin Tiorfan Lyrica Arcoxia Malaria-Impfstoff Anti-Interleukin-AK Intrinsa (Testosteron-Pflaster für Frauen) Tipranavir BAY 59-7939 Zonisamid (Zonegran®) Muraglitazar (Pargluva)

Osteoprotegerin Atomoxetin (Strattera) Ertapenem Thalidomid Tadalafil (Cialis) Angiogenese-Hemmer Nuvaring Cera Vardenafil (Levitra) Mitoxantron (Ralenova) Mometason (Asmanex Twisthaler) Natalizumab Roflumilast Enfuvirtid (Fuzeon) FSME-Immun Exenatide Ciclesonide Bortezomib Topiramat rHuKGF Bevacizumab Liraglutide Niaspan Aripiprazol Entecavir (Baraclude®) Yondelis Flumist Omalizumab Palonosetron EGF Temodal Evra Escitalopram (Cipralex®) Everolimus Licofelone Darmhormon-pyy Duloxetin (Yentreve) Ivabradin Efalizumab Fusionsprotein-ctla41g sargramostim forsteo

Dronabinol Eleptripan (Relpax) Encepur Anakinra (Kineret) Arsen (Trisenox) Fondaparinux (Arixtra) Ebastin (Ebastel) Ziprasidon (Zeldox) Tacrolimus (Protopic) Bimatoprost (Lumigan) Bosentan (Tracleer) Valganciclovir (Valcyte) Peg-Interferon (Pegasys) Oseltamivir (Tamiflu) Parecoxib (Dynastat) Caspofungin Tiotropiumbromid (Spiriva) Tegaserod (Zelnorm) Iressa Olmesartan (Olmetec) Memantin (Axura) Adalimumab-p Negativliste Pegfilgrastim (Neulasta) Darbepoetin (Aranesp) Eplerenon (Inspra) Pimecrolimus (Elidel) Xigris Adefovir BILN 2061 Frovatriptan (Allegro) Teriparatid (Forteo) Ezetimib (Ezetrol)

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